Which syndrome is characterized by a narrow high palate?

Apert syndrome is characterized by a range of craniofacial abnormalities, one of which is a narrow high palate. This condition results from mutations in the FGFR2 or FGFR1 genes, leading to the premature fusion of skull bones (craniosynostosis), which affects the shape and structure of the face and mouth. The narrow high palate is a common dental finding in individuals with this syndrome, often complicating oral and orthodontic health as well as impacting speech development due to the restricted space in the oral cavity.

Hallermann-Strieff Syndrome, Crouzon syndrome, and Down syndrome do present with various craniofacial features, but they are not primarily known for a narrow high palate as is characteristic of Apert syndrome. Hallermann-Strieff includes features such as miniature-size facial structure and dental anomalies, while Crouzon syndrome is known for ocular and skull deformities, and Down syndrome has its own distinct features ranging from intellectual disability to specific physical traits, but does not emphasize nasal or palatal characteristics like Apert syndrome does.