Which of the following syndromes is least likely to be associated with supernumerary teeth?

Supernumerary teeth, which are additional teeth beyond the normal series, can be associated with various syndromes. Sturge-Weber syndrome is primarily characterized by a facial capillary malformation known as a port-wine stain, along with neurological and dental complications, but it is not commonly linked to the development of supernumerary teeth.

In contrast, Apert syndrome, Cleidocranial dysplasia, and Gardner syndrome all exhibit a stronger correlation with the presence of supernumerary teeth. Apert syndrome is characterized by craniosynostosis and often includes dental anomalies such as supernumerary teeth. Cleidocranial dysplasia is known for its significant dental abnormalities, including the presence of multiple supernumerary teeth due to the absence of the clavicles and associated dental development issues. Gardner syndrome, a condition that includes a variety of dental abnormalities, is also associated with supernumerary teeth as well as other oral manifestations.

Thus, the link between Sturge-Weber syndrome and supernumerary teeth is weak, making it the least likely of the options provided.