What late symptoms may indicate an overdose of local anesthetics?

Drowsiness and circumoral numbness are significant indicators of local anesthetic overdose. When local anesthetics are administered in excessive amounts, they can affect the central nervous system, leading to symptoms that include drowsiness, confusion, and even eventual respiratory depression. Circumoral numbness refers to tingling or numbness around the mouth, which is a classic early sign of systemic absorption of local anesthetic, often preceding more severe central nervous system symptoms.

The presence of these symptoms suggests that the anesthetic agent has moved beyond the intended site and is affecting the brain and peripheral nervous system. Recognizing these signs early can be critical in managing an overdose situation effectively, as immediate action can prevent progression to more severe complications such as seizures or cardiovascular issues.