What is the name of the condition characterized by diffuse, white, thickened adherent and wrinkled oral mucosa?

The condition characterized by diffuse, white, thickened adherent and wrinkled oral mucosa is known as White Sponge Nevus. This condition is a genetic disorder that leads to a harmless proliferation of the oral mucosal epithelium, often resulting in painless, white lesions.

In White Sponge Nevus, the thickened mucosa is typically associated with a specific appearance where the lesions are bilateral and symmetrical. The change in texture and color occurs due to a mutation affecting keratinocytes, leading to the accumulation of keratin in the oral mucosa. This is different from other conditions, which may also involve white lesions but have distinct characteristics or etiologies.

Leukoplakia refers to white patches that cannot be scraped off and could potentially be precancerous, while Lichen Planus is an autoimmune condition that presents with white striae or papules usually accompanied by symptoms such as itching. Candidiasis, on the other hand, is a fungal infection that generally leads to creamy white lesions that can be wiped off, revealing a red, inflamed mucosa beneath. Each of these has varying clinical presentations and underlying causes, distinguishing them from White Sponge Nevus.