What is the adult dosage for Ampicillin given for SBE prophylaxis IM/IV?

The correct dosage of Ampicillin for the prophylaxis of infective endocarditis (previously known as subacute bacterial endocarditis or SBE) is 2 g administered intravenously (IV) or intramuscularly (IM). This dosage is established based on clinical guidelines that recommend an effective level of the antibiotic to adequately prevent infections in individuals at high risk, particularly before dental or surgical procedures.

Using 2 g of Ampicillin ensures that there is a sufficient concentration of the drug in the bloodstream to effectively combat potential bacteria that could enter the bloodstream during procedures. This prophylactic approach is important for individuals who have certain heart conditions that predispose them to endocarditis.

The other dosages listed, such as 1 g, 500 mg, and 750 mg, do not meet the recommended guidelines for SBE prophylaxis and therefore would not provide the same level of protection against potential infections. The 2 g dosage is specifically chosen to align with current medical recommendations and evidence on effective prophylaxis for this condition.